The SYRCLE risk of bias tool is a widely used way to judge internal validity in a systematic review of animal intervention studies. It has ten entries that cover selection, performance, detection, attrition and reporting bias plus a catch-all for other problems, and every entry is rated low, high or unclear. This guide explains each entry, compares the tool with the CAMARADES quality checklist, and…
The STREGA checklist is the reporting guideline for genetic association studies. The name stands for STrengthening the REporting of Genetic Association studies, and Little and colleagues published it in 2009 as an extension of the STROBE statement [1]. STROBE has 22 items, and STREGA adds genetics-specific text to 12 of them [1]. The additions deal with problems that rarely arise in other observational designs, such…
The CHERRIES checklist, short for Checklist for Reporting Results of Internet E-Surveys, is the reporting guideline for questionnaires that people complete on the web. Gunther Eysenbach published it in the Journal of Medical Internet Research in 2004 as a table of 30 items in eight categories, and a 2012 correction fixed the formulas for three response measures.1,2 We found no revised or extended version, so…
.tp{color:#333333 !important;line-height:1.7 !important;margin:0 0 16px 0 !important} .th2{color:#0d2137 !important;margin:36px 0 14px 0 !important;line-height:1.3 !important} .th3{color:#0d2137 !important;margin:24px 0 10px 0 !important;line-height:1.35 !important} .tl{color:#003057 !important;font-weight:600;text-decoration:underline} .tt{border-collapse:collapse;width:100%} .tt th{background-color:#0d2137 !important;color:#ffffff !important;text-align:left;padding:10px 12px !important;font-size:.9rem;border:1px solid #0d2137 !important} .tt td{color:#333333 !important;padding:9px 12px !important;font-size:.9rem;vertical-align:top;border:1px solid #d8dee6 !important;line-height:1.5} .tt td.w{background-color:#ffffff !important} .tt td.g{background-color:#f6f9fc !important} .tt td.rg{background-color:#f1f8f3 !important} .tt td.rp{background-color:#fff9ec !important} .tt td.rn{background-color:#fef1f1 !important} .tt td.rj{background-color:#f0f4fc !important} .tt td.vg{background-color:#d9eee0 !important;color:#14532d !important;font-weight:700} .tt td.vp{background-color:#ffecc2…
The ARRIVE 2.0 checklist has 21 items, and ten of them decide whether a reviewer can trust an animal study at all. Those ten, called the Essential 10, cover the study design, sample size, exclusions, randomisation, blinding, outcomes, statistics, animals, procedures and results. This guide applies every one of them to a real open-access rat study, names the section where each answer sits, and marks…
