Description
Systematic Review & Meta-Analysis (Industry-Sponsored)
Comprehensive evidence synthesis for industry-sponsored programs, supporting regulatory submissions, label claims and health technology assessments. We deliver PRISMA 2020-compliant systematic reviews with quantitative meta-analysis, from a PROSPERO-registered protocol through to a full journal-ready manuscript.
Service Details
| Timeline | Standard: 16-24 weeks | Rapid review: 8-12 weeks |
| Best for | Regulatory submission support (Module 2.5), HTA dossiers, label expansion evidence, competitive positioning and guideline development support |
| Standards | PRISMA 2020, Cochrane Handbook, GRADE, GPP 2022, PROSPERO |
| What you receive | Everything from a PROSPERO-registered protocol to a full journal-ready manuscript (see Deliverables below) |
Compliance Framework
- PRISMA 2020 – Reporting guideline
- Cochrane Handbook – Methodological standards
- GRADE – Evidence quality assessment
- GPP 2022 – Industry-sponsored review ethics
- PROSPERO – Protocol registration
Deliverables
- PROSPERO-registered protocol
- Comprehensive search strategy (MEDLINE, Embase, Cochrane, etc.)
- Study selection with PRISMA flow diagram
- Data extraction tables
- Risk of bias assessment (Cochrane RoB 2, ROBINS-I)
- Meta-analysis with forest plots
- Heterogeneity and sensitivity analyses
- Publication bias assessment
- GRADE evidence summary tables
- Full manuscript (journal-ready)
Applications
- Regulatory submission support (Module 2.5)
- HTA dossiers
- Label expansion evidence
- Competitive positioning
- Guideline development support
How It Works
- Tell us your research question and how the review will be used, for example in a regulatory submission, an HTA dossier or a journal publication
- We develop and register the protocol on PROSPERO, then run the search, study selection, data extraction and risk of bias assessment
- We run the meta-analysis with heterogeneity, sensitivity and publication bias analyses, and summarize the evidence with GRADE
- You review the draft manuscript and evidence tables, we revise based on your feedback, and you receive the full journal-ready manuscript
Which Service Do You Need?
This service is built for industry-sponsored reviews that support regulatory, HTA or label decisions. For a systematic review and meta-analysis aimed at journal publication, see Professional Meta-Analysis & Systematic Review Services. To compare multiple interventions in one analysis, see Network Meta-Analysis Service. If you only need the quality assessment of included studies, see Risk of Bias Assessment.
Try It Free First
Want to explore your data before ordering? Try our free Meta-Analysis Calculator (forest plot and heterogeneity), the Publication Bias Calculator, or the Reporting Guideline Flow Diagram Generator for a PRISMA flow diagram.
Frequently Asked Questions
Which databases do you search?
The comprehensive search strategy covers MEDLINE, Embase, Cochrane and other relevant databases.
How is risk of bias assessed?
With Cochrane RoB 2 and ROBINS-I.
How long does it take?
The standard timeline is 16-24 weeks. A rapid review takes 8-12 weeks.
Can the review support a regulatory submission or HTA dossier?
Yes. Applications include regulatory submission support (Module 2.5), HTA dossiers, label expansion evidence, competitive positioning and guideline development support.
Get started: add this service to your cart, or email co*****@*******se.com with your research question and intended use.
