Did you know antidepressants started in the 1950s to fight depression? This mood disorder brings deep sadness and hopelessness. These drugs change brain chemicals called neurotransmitters. They’re now used for many conditions in the U.S. Understanding Antidepressants Antidepressants are medications used to treat depression and other mental health conditions. They work by altering the balance of neurotransmitters in the brain, which are chemicals that affect…